SERCLUTAMAB TALIRINE

UNII:	7W0O278T12
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	SERCLUTAMAB TALIRINE
GSRS Full Record:	7W0O278T12 i

2140174-56-5
ABBV-321
ANTI-EGFR/PBD ANTIBODY-DRUG CONJUGATE ABBV-321
IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS EGFR (EPIDERMAL GROWTH FACTOR RECEPTOR, RECEPTOR TYROSINE-PROTEIN KINASE ERBB-1, ERBB1, HER1, HER-1, ERBB)), MONOCLONAL ANTIBODY CONJUGATED TO THE PYRROLOBENZODIAZEPINE (PDB) DIMER SGD-1882GAMMA1 HEAVY CHAIN (1-446) (VH (HOMO SAPIENS IGHV4-30-4*01 (81.4%)-(IGHD)-IGHJ4*01 (92.9%)) (9.7.9) (1-116)-HOMO SAPIENS IGHG1*03V, G1M3>G1M17, NG1M1 (CH1 R120>K (213) (117-214), HINGE (215-229), CH2 S3>C (238) (230-339), CH3 E12 (355), M 14 (357) (340-444), CHS (445-446)) (117-446)), (219-214')-DISULFIDE WITH KAPPA LIGHT CHAIN (1'-214') (V-KAPPA (MUS MUSCULUS IGKV14-100*01 (86.3%)-IGKJ1*01 (100%)/HOMO SAPIENS IGKV1-12*01 (74.7%)-IGKJ4*01 (90.9%)) (6.3.9) (1'-107')-HOMO SAPIENS IGKC*01 (100%), KM3 A45.1 (153), V101 (191) (108'-214'))DIMER (225-225'':228-228'')-BISDISULFIDECONJUGATED, ON TWO SITE-SPECIFIC DRUG ATTACHMENT ENGINEERED CYSTEINES (C238, C238''), TO PYRROLOBENZODIAZEPINE (PDB) DIMERS SGD-1882, VIA A CATHEPSIN-CLEAVABLE MALEIMIDOCAPROYLVALINE-ALANINE (MC-VAL-ALA) TYPE LINKER
SERCLUTAMAB TALIRINE [USAN]
Serclutamab talirine [WHO-DD]
serclutamab talirine [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

SERCLUTAMAB TALIRINE

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