TAZLESTOBART

UNII:	7QW97A6ZTH
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	TAZLESTOBART
GSRS Full Record:	7QW97A6ZTH i

2850355-80-3
H-gamma1 heavy chain humanized (1-448) [VH (Homo sapiens IGHV3-30*01 (94.9%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.11] (26-33.51-58.97-107)) (1-118) -Homo sapiens IGHG1*03, G1m3, nG1m1 CH1 R120, CH3 E12, M14, G1v6 CH2 A85.4, A118, A119 (CH1 R120 (215) (119-216), hinge 1-15 (217-231), CH2 S85.4>A (299), E118>A (334), K119>A (335), (232-341), CH3 E12 (357), M14 (359) (342-446), CHS (447-448)) (119-448)], (221-215')-disulfide with L-kappa light chain humanized (1'-215') [V-KAPPA (Homo sapiens IGKV3-20*01 (97.9%) -IGKJ1*01 (100%), CDRI-MGT [7.3.9] (27'-33'.51'-53'.90'-98')) (1'-108') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (154'), V101 (192') (109'-215')]; dimer (227-227'':230-230'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1, glycoform alfa
Immunoglobulin G1 [299-alanine,334-alanine,335-alanine], anti-(human cytotoxic T-lymphocyte-associated protein 4) (human-Mus musculus monoclonal IMM27M γ-chain), disulfide with human-Mus musculus monoclonal IMM27M κ-chain, dimer
Tazlestobart
immunoglobulin G1-kappa, anti-[Homo sapiens CTLA4 (cytotoxic Tlymphocyte associated protein 4, CTLA-4, CD152)], humanized monoclonal antibody
tazlestobart [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

TAZLESTOBART

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