ARITINERCEPT

UNII:	7L6F3P97K5
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	ARITINERCEPT
GSRS Full Record:	7L6F3P97K5 i

3057276-00-0
Aritinercept
aritinercept [INN]
human tumor necrosis factor receptor superfamily member 17 (TNFRSF17, B-cell maturation protein, BCMA, CD269, Uniprot: Q02223) extracellular domain fragment (5-49, 1-45 in the currentsequence) variant (S16>H12 , L18>I14 , H19>R15, S44>G40) fused at the C-terminus via peptide linker 46GGGGSA51 to a human immunoglobulin G4 (IgG4) Fc fragment (h-CH2-CH3-CHS domains) (52-280) [Homo sapiens IGHG4*01 (hinge S61>P (52-63), CH2 F67>A, L68>A (64-173), CH3 L278>P(174-278), CHS (279-280))] dimer (59-59':62-62')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1, glycoform alfa

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

ARITINERCEPT

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