LATOVETCEL

UNII:	74A8KT7B4S
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	LATOVETCEL
GSRS Full Record:	74A8KT7B4S i

Equine allogeneic mesenchymal stem/stromal cells (MSCs) isolated from peripheral blood mononuclear cells (PBMCs) collected from donor horses. The MSCs are selected for by growing the PBMCs in media containing fetal bovine serum (FBS) and dexamethasone and then further expanded in media containing FBS (The final cells are characterized by their spindle shaped morphology, and by expression of the cellular surface markers CD90 (≥95%) and CD44 (≥85%) and absence of MHC class II expression (≤2%). The cells secrete prostaglandin E2 (PGE2) and interleukin 6 (IL-6) and can decrease proliferation (>85%) in a mixed lymphocyte reaction assay with concanavalin A (ConA)-stimulated canine PMBCs)
Latovetcel
latovetcel [INN]

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UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

LATOVETCEL

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