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MIPASETAMAB UZOPTIRINE

UNII:71KV7F609O
Type:INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:MIPASETAMAB UZOPTIRINE
GSRS Full Record:
71KV7F609O
i

  • 2304799-73-1
  • ADCT-601
  • IMMUNOGLOBULIN G1, ANTI-(HUMAN RECEPTOR TYROSINE KINASE AXL) (HUMAN-MUS MUSCULUS MONOCLONAL 1H12 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL 1H12 .KAPPA.-CHAIN, DIMER, 302,302'-BIS(N-(O-2-(ACETYLAMINO)-6-AZIDO-2,6-DIDEOXY-.BETA.-D-GALACTOPYRANOSYL-(1->4)-O-(6-DEOXY-.ALPHA.-L-GALACTOPYRANOSYL-(1->6))-2-(ACETYLAMINO)-2-DEOXY-.BETA.-D-GLUCOPYRANOSYL)-L-ASPARAGINE), CLICK REACTION PRODUCT WITH N-(10,10-DIOXIDO-1,12-DIOXO-14-((1.ALPHA.,8.ALPHA.,9.BETA.)-BICYCLO(6.1.0)NON-4-YN-9-YL)-3,6,13-TRIOXA-10-THIA-9,11-DIAZATETRADEC-1-YL)-L-VALYL-N-(4-(((((11S,11AS)-8-((5-(((11AS)-5,11A-DIHYDRO-7-METHOXY-2-METHYL-5-OXO-1H-PYRROLO(2,1-C)(1,4)BENZODIAZEPIN-8-YL)OXY)PENTYL)OXY)-11,11A-DIHYDRO-11-HYDROXY-7-METHOXY-2-METHYL-5-OXO-1H-PYRROLO(2,1-C)(1,4)BENZODIAZEPIN-10(5H)-YL)CARBONYL)OXY)METHYL)PHENYL)-L-ALANINAMIDE
  • IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS AXL (AXL RECEPTOR TYROSINE KINASE, TYROSINE-PROTEIN KINASE RECEPTOR UFO)), HUMANIZED MONOCLONAL ANTIBODY CONJUGATED TO THE PYRROLOBENZODIAZEPINE (PBD) DIMER, SG3199 (MIPASETAMAB UZOPTIRINE)
  • IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS TYROSINE-PROTEIN KINASE RECEPTOR UFO (AXL ONCOGENE; EC=2.7.10.1)); HUMANIZED MONOCLONAL ANTIBODY CONJUGATED TO THE PYRROLOBENZODIAZEPINE (PDB) DIMER, SG3199; .GAMMA.1 HEAVY CHAIN HUMANIZED (1-451) (VH HUMANIZED (HOMO SAPIENS IGHV3-30*03 (93%)-(IGHD)-IGHJ4*01 (92%)) (8.8.15) (1-122) HOMO SAPIENS IGHG1*03 (CH1(R97>K(219)), CH3(K107>DEL(452))) (123-451)), (225-215')-DISULFIDE WITH .KAPPA. LIGHT CHAIN HUMANIZED (1'-215') (HUMANIZED V-KAPPA (HOMO SAPIENS IGKV3-11*01 (84%)-IGKJ4*01 (91%))(7.3.9) (1'-108')-HOMO SAPIENS IGKC*01 (109'-215')); DIMER (231-231'':234-234'')-BISDISULFIDE, PRODUCED IN CHINESE CHO CELLS, GLYCOFORM ALFA; CONJUGATED ON THE TWO GLYCOENGINEERED ASN-302 AND ASN-302'', VIA A SPACER AND CLEAVABLE VALYL-ALANYL LINKER, TO THE CYTOTOXIC PYRROLOBENZODIAZEPINE (PBD) DIMER, SG3199
  • MIPASETAMAB UZOPTIRINE [USAN]
  • Mipasetamab uzoptirine [WHO-DD]
  • mipasetamab uzoptirine [INN]




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