DIVESIRAN

UNII:	6WZ4756CFE
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	DIVESIRAN
GSRS Full Record:	6WZ4756CFE i

2646704-10-9
Divesiran
Divesiran [WHO-DD]
Manusiran
RNA, (Am-sp-(2′-deoxy-2′-fluoro)A-sp-Cm-(2′-deoxy-2′-fluoro)C-Am-(2′-deoxy-2′-fluoro)G-Am-(2′-deoxy-2′-fluoro)A-Gm-(2′-deoxy-2′-fluoro)A-Am-(2′-deoxy-2′-fluoro)G-Cm-(2′-deoxy-2′-fluoro)A-Gm-(2′-deoxy-2′-fluoro)G-Um-sp-(2′-deoxy-2′-fluoro)G-sp-Am), complex with RNA ((2′-deoxy-2′-fluoro)U-Cm-(2′-deoxy-2′-fluoro)A-Cm-(2′-deoxy-2′-fluoro)C-Um-(2′-deoxy-2′-fluoro)G-Cm-(2′-deoxy-2′-fluoro)U-Um-(2′-deoxy-2′-fluoro)C-Um-(2′-deoxy-2′-fluoro)U-Cm-(2′-deoxy-2′-fluoro)U-Gm-(2′-deoxy-2′-fluoro)G-sp-Um-sp-(2′-deoxy-2′-fluoro)U) 5′-[O-[19-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-7,7-bis[12-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-7-mercapto-7-oxido-2,6,8-trioxa-7-phosphadodec-1-yl]-14-mercapto-14-oxido-5,9,13,15-tetraoxa-14-phosphanonadec-1-yl] hydroxy phosphate] (1:1)
all-P-ambo-5'-O-{21-[(2-acetamido-2-deoxy-β-D -galactopyranosyl)oxy]-9,9-bis{12-[(2-acetamido-2-deoxy-β-D -galactopyranosyl)oxy]-7-hydroxy-7-sulfanylidene-2,6,8-trioxa-7λ 5 -phosphadodecan-1-yl}-1,16-dihydroxy-1,16-bis(sulfanylidene)-2,7,11,15,17-pentaoxa-1λ 5,16λ 5-diphosphahenicosan-1-yl}-2'-deoxy-2'-fluorouridylyl-(3'→5')-2'-O-methylcytidylyl-(3'→5')-2'-deoxy-2'-fluoroadenylyl-(3'→5')-2'-O-methylcytidylyl-(3'→5')-2'-deoxy-2'-fluorocytidylyl-(3'→5')-2'-O-methyluridylyl-(3'→5')-2'-deoxy-2'-fluoroguanylyl-(3'→5')-2'-O-methylcytidylyl-(3'→5')-2'-deoxy-2'-fluorouridylyl-(3'→5')-2'-O-methyluridylyl-(3'→5')-2'-deoxy-2'-fluorocytidylyl-(3'→5')-2'-O-methyluridylyl-(3'→5')-2'-deoxy-2'-fluorouridylyl-(3'→5')-2'-O-methylcytidylyl-(3'→5')-2'-deoxy-2'-fluorouridylyl-(3'→5')-2'-O-methylguanylyl-(3'→5')-2'-deoxy-2'-fluoro-P-thioguanylyl-(3'→5')-2'-O-methyl-P-thiouridylyl-(3'→5')-2'-deoxy-2'-fluorouridine, duplex with all-P-ambo-2'-O-methyl-P-thioadenylyl-(3'→5')-2'-deoxy-2'-fluoro-P-thioadenylyl-(3'→5')-2'-O-methylcytidylyl-(3'→5')-2'-deoxy-2'-fluorocytidylyl-(3'→5')-2'-O-methyladenylyl-(3'→5')-2'-deoxy-2'-fluoroguanylyl-(3'→5')-2'-O-methyladenylyl-(3'→5')-2'-deoxy-2'-fluoroadenylyl-(3'→5')-2'-O-methylguanylyl-(3'→5')-2'-deoxy-2'-fluoroadenylyl-(3'→5')-2'-O-methyladenylyl-(3'→5')-2'-deoxy-2'-fluoroguanylyl-(3'→5')-2'-O-methylcytidylyl-(3'→5')-2'-deoxy-2'-fluoroadenylyl-(3'→5')-2'-O-methylguanylyl-(3'→5')-2'-deoxy-2'-fluoroguanylyl-(3'→5')-2'-O-methyl-P-thiouridylyl-(3'→5')-2'-deoxy-2'-fluoro-P-thioguanylyl-(3'→5')-2'-O-methyladenosine
divesiran [INN]

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UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

DIVESIRAN

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