CENVACIBART

UNII:	6NM5PD4YTH
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	CENVACIBART
GSRS Full Record:	6NM5PD4YTH i

3008610-21-4
CENVACIBART [USAN]
Cenvacibart
H-gamma4 heavy chain Homo sapiens (1-445) [VH (Homo sapiens IGHV3-11*01 (91.7%) -(IGHD) -IGHJ3*02 (100%), CDR-IMGT [8.8.11] (26-33.51-58.97-107)) (1-118) -Homo sapiens IGHG4*01, nG4m(a) CH2 L92, 12-G4v5 h P10(CH1 (119-216), hinge 1-12 S10>P (226) (217-228), CH2 L92 (307) (229-338), CH3 (339-443), CHS (444-445)) (119-445)], (132-214')-disulfide with L-kappa light chain Homo sapiens (1'-214') [VKAPPA (Homo sapiens IGKV1-33*01 (95.8%) -IGKJ2*02 (100%), CDR-IMGT [6.3.9] (27'-32'.50'-52'.89'-97')) (1'-107') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (153'), V101 (191')) (108'-214')]; dimer (224-224'':227-227'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1, glycoform alfa
Immunoglobulin G4 [226-proline], anti-(human blood-coagulation factor XI/XIa) (human monoclonal REGN7508 γ4-chain), disulfide with human monoclonal REGN7508 κ-chain, dimer
Immunoglobulin G4-kappa, anti-[Homo sapiens F11 (coagulation factor 11, coagulation factor XI, FXI, plasma thromboplastin antecedent, PTA)], Homo sapiens monoclonal antibody; H-gamma4 heavy chain Homo sapiens (1-445) [VH (Homo sapiens IGHV3-11*01 (91.7%) -(IGHD) -IGHJ3*02 (100%), CDR-IMGT [8.8.11] (26-33.51-58.97-107)) (1-118) -Homo sapiens IGHG4*01, nG4m(a) CH2 L92, 12-G4v5 h P10(CH1 (119-216), hinge 1-12 S10>P (226) (217-228), CH2 L92 (307) (229-338), CH3 (339-443), CHS (444-445)) (119-445)], (132-214')-disulfide with L-kappa light chain Homo sapiens (1'-214') [VKAPPA (Homo sapiens IGKV1-33*01 (95.8%) -IGKJ2*02 (100%), CDR-IMGT [6.3.9] (27'-32'.50'-52'.89'-97')) (1'-107') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (153'), V101 (191')) (108'-214')]; dimer (224-224'':227-227'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1, glycoform alfa
REGN-7508
REGN7508
cenvacibart [INN]
immunoglobulin G4-kappa, anti-[Homo sapiens F11 (coagulation factor 11, coagulation factor XI, FXI, plasma thromboplastin antecedent, PTA)], Homo sapiens monoclonal antibody

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

CENVACIBART

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