LUMISTOBART

UNII:	6GCR77W6UZ
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	LUMISTOBART
GSRS Full Record:	6GCR77W6UZ i

2851923-91-4
BR-105
BR105
H-gamma1 heavy chain humanized (1-448) [VH (Homo sapiens IGHV4-31*02 (93.9%) -(IGHD) -IGHJ4*01 (86.7%) L123>T (113), CDR-IMGT [9.7.11] (26-34.52-58.97-107)) (1-118) -Homo sapiens IGHG1*03v, G1m3>G1m17, nG1m1 CH1 K120, CH3 E12, M14, G1v29 CH2 A84.4 (CH1 R120>K (215) (119-216), hinge 1-15 (217-231), CH2 N84.4>A (298) (232-341), CH3 E12 (357), M14 (359) (342-446), CHS (447-448)) (119-448)], (221-220')-disulfide with L-kappa light chain humanized (1'-220') [V-KAPPA (Homo sapiens IGKV4-1*01 (91.1%) -IGKJ2*01 (100%), CDR-IMGT [12.3.9] (27'-38'.56'-58'.95'-103')) (1'-113') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (159'), V101 (197') (114'-220')]; dimer (227-227'':230-230'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-S, non-glycosylated
Immunoglobulin G1, anti-(human signal regulatory protein α) (human-Mus musculus monoclonal BR105 γ1-chain), disulfide with human-Mus musculus monoclonal BR105 κ-chain, dimer
Lumistobart
immunoglobulin G1-kappa, anti-[Homo sapiens SIRPA (signal regulatory protein alpha, SHPS1, protein tyrosine phosphatase nonreceptor type substrate 1, PTPNS1, SIRP, SIRP alpha, CD172a)], humanized monoclonal antibody
lumistobart [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

LUMISTOBART

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