IPSOPRUBART

UNII:	6DT5Q4GT2M
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	IPSOPRUBART
GSRS Full Record:	6DT5Q4GT2M i

3035552-25-8
ELA-026
ELA026
H-gamma1 heavy chain Homo sapiens (1-448) [VH (Homo sapiens IGHV4-4*02 (100%) -(IGHD) -IGHJ1*01 (100%), CDR-IMGT [9.7.11] (26-34.52-58.97-107)) (1-118) -Homo sapiens IGHG1*01, G1m17,1 CH1 K120, CH3 D12, L14, 3-G1v13 CH2 A1.1, D3, E117 (CH1 K120 (215), V121>A (216) (119-215), hinge 1-15 (216-231), CH2 G1.1>A (237), S3>D (240), I117>E (333) (232-341), CH3 D12 (357), L14 (359) (342-446), CHS (447-448)) (119-448)], (221-219')-disulfide with L-kappa light chain Homo sapiens (1'-219') [V-KAPPA (Homo sapiens IGKV2-28*01 (96.0%) -IGKJ1*01 (100%), CDR -IMGT [11.3.9] (27'-37'.55'-57'.94'-102')) (1'-112') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (158'), V101 (196')) (113'-219')]; dimer (227-227'':230-230'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1, glycoform alfa
Immunoglobulin G1 [237-alanine,240-aspartic acid,333-glutamic acid], anti-(human signal regulatory proteins (SIRPα/SIRPβ/ SIRPγ)) (human monoclonal ELA026 γ1-chain), disulfide with human monoclonal ELA026 κ-chain, dimer
Ipsoprubart
immunoglobulin G1-kappa, anti-[Homo sapiens SIRPA (signal regulatory protein alpha, SHPS1, protein tyrosine phosphatase non-receptor type substrate 1, PTPNS1, SIRP, SIRP alpha, CD172a)], Homo sapiens monoclonal antibody (ipsoprubart)
ipsoprubart [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

IPSOPRUBART

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