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IVATMERAN

UNII:6DT57U6VP8
Type:INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:IVATMERAN
GSRS Full Record:

  • 2924631-87-6
  • Ivatmeran
  • RNA (recombinant 5′-(m7G-(5′→5′)-ppp-Gm)-capped all uridine→N1-methylpseudouridine-substituted 5′-untranslated region plus human propionyl-CoA carboxylase β subunit plus 3′-untranslated region-containing microRNA-142 binding sites plus poly(A)-tailed messenger CX-032065), inner salt
  • ivatmeran [INN]
  • messenger RNA (mRNA), 5'(m 7 G-(5′→5′)-ppp-Gm)-capped, encoding codon-optimised human propionyl-CoA carboxylase subunit beta (PCCB), flanked by 5' and 3' untranslated regions (UTR) followed by a 3' polyadenylation (polyA) tail and concluded by a 5-nucleotide XbaI scar. The 3' UTR contains three microRNA-142 (miR-142) binding sites. Contains N-methylpseudouridine instead of uridine (all-U>m 1Ψ)



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