MOZISTOBART

UNII:	67RJK4R3RW
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	MOZISTOBART
GSRS Full Record:	67RJK4R3RW i

2852752-92-0
AB-125
H-gamma1 heavy chain humanized (1-460) [VH (Homo sapiens IGHV3-48*03 (89.8%) -(IGHD) -IGHJ4*01 (85.7%) Q120>R (115), CDR-IMGT [8.8.16] (26-33.51-58.97-112)) (1-123) -Homo sapiens IGHG1*03v, G1m3>G1m17, nG1m1 CH1 K120, CH3 E12, M14, G1v14-1 CH2 A1.3, A1.2, A1 (CH1 R120>K (220) (124-221), hinge 1-15 (222-236), CH2 L1.3>A (240), L1.2>A (241), G1>A (243) (237-346), CH3 E12 (362), M14 (364) (347-451), CHS K2>del (452), fused 8-mer RPQGFGPP (453-460)) (124-460)], (226-214')-disulfide with L-kappa light chain humanized (1'-214') [V-KAPPA (Homo sapiens IGKV1-39*01 (87.4%) -IGKJ2*02 (100%), CDR-IMGT [6.3.9] (27'-32'.50'-52'.89'-97')) (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153'), V101 (191') (108'-214')]; dimer (232-232'':235-235'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, derived from the cell line CHOK1, glycoform alfa
Immunoglobulin G1 [240-alanine,241-alanine,243-alanine], anti-(human/Macaca fascicularis sialic acid-binding Ig-like lectin 2) (human-Mus musculus monoclonal Ab-125 γ1-chain) fusion protein with peptide (RPQGFGPP), disulfide with human-Musculus monoclonal Ab-125 κ-chain, dimer
Mozistobart
immunoglobulin G1-kappa, anti-[Homo sapiens CD22 (sialic acid binding Ig-like lectin 2, SIGLEC2, SIGLEC-2, B-lymphocyte cell adhesion molecule, BL-CAM, Leu-14)], humanized monoclonal antibody
mozistobart [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

MOZISTOBART

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