FDA official logo
GSRS logoPFDA official logo

TAMBOTATUG PELITECAN

UNII:66NNR5T69Q
Type:INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:TAMBOTATUG PELITECAN
GSRS Full Record:
66NNR5T69Q
i

  • 2925042-80-2
  • B386,
  • Immunoglobulin G1, anti-(human B7 homolog protein B7H3) (human monoclonal YL201 γ1-chain), complex with human monoclonal YL201 κ-chain, dimer, octakis(thioether) with N-[6-(2-mercapto-5-pyrimidinyl)-1-oxo-5-hexyn-1-yl]-L-valyl-N6,N6-dipropyl-L-lysyl-N-[[3-[(7S)-7-ethyl-7,8,11,13-tetrahydro-7-hydroxy-8,11-dioxo-10H-1,3-dioxolo[4,5-g]pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin-14-yl]propoxy]methyl]glycinamide
  • TAMBOTATUG PELITECAN [USAN]
  • Tambotatug Pelitecan
  • YL 201 [WHO-DD]
  • YL-201
  • YL201
  • YL201-DS
  • immunoglobulin G1-kappa, anti-[Homo sapiens CD276 (B7H3, B7-H3, B7-related protein 2, B7RP2, B7RP-2, B7 homolog 3, B7 homologue 3)], Homo sapiens monoclonal antibody; conjugated on an average of eight cysteinyl residues to pelitecan groups, comprising a linker and a camptothecin derivative (a topoisomerase I inhibitor); H-gamma1 heavy chain Homo sapiens (1-450) [VH (Homo sapiens IGHV3-23*01 (96.9%) -(IGHD) -IGHJ4*01 (93.3%), CDR-IMGT [8.8.13] (26-33.51-58.97-109)) (1-120) -Homo sapiens IGHG1*01 (100%) G1m17,1 CH1 K120, CH3 D12, L14 (CH1 K120(217) (121-218), hinge 1-15 (219-233), CH2 (234-343), CH3 D12 (359), L14 (361) (344-448), CHS (449-450)) (121-450)], (223-215')-disulfide with L-kappa light chain Homo sapiens (1'-215') [V-KAPPA (Homo sapiens IGKV3-20*01 (91.7%) -IGKJ4*01 (100%), CDR-IMGT [7.3.9] (27'-33'.51'-53'.90'-98')) (1'-108') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (154'), V101 (192')) (109'-215')]; dimer (229-229'':232-232'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa; substituted at the sulfur atoms of the L -cysteinyl residues 223, 229, 232, 215', 223'', 229'', 232'' and 215''' with 5-[(11S,14S)-11-[4-(dipropylamino)butyl]-1-[(7S)-7-ethyl-7-hydroxy-8,11-dioxo-7,8,11,13-tetrahydro-2H,10H-[1,3]dioxolo[4,5-g]pyrano[3',4':6,7]indolizino[1,2-b]quinolin-14-yl]-7,10,13,16-tetraoxo-14-(propan-2-yl)-4-oxa-6,9,12,15-tetraazahenicos-20-yn-21-yl]pyrimidin-2-yl (pelitecan) groups (tambotatug pelitecan)
  • tambotatug pelitecan [INN]




UNII - 66NNR5T69Q | UNII Search Service