ROVOCTOCOGENE DURPARVOVEC

UNII:	63QD0BX9B4
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	ROVOCTOCOGENE DURPARVOVEC
GSRS Full Record:	63QD0BX9B4 i

2163074-26-6
A RECOMBINANT INTRONLESS NON-REPLICATING ADENO-ASSOCIATED VIRUS 2 VECTOR (AAV2) WITH A BIO-ENGINEERED CAPSID DERIVED BY DNA SHUFFLING OF 10 AAV CAPSID SEQUENCES (AAV1, 2, 3B, 4, 5, 6 8, 9, AVIAN AND BOVINE AAV) FOLLOWED BY IN VIVO SELECTION IN FAH//RAG2//IL2RG/ (FRG) MICE PARTIALLY REPOPULATED WITH HUMAN HEPATOCYTES. THE VECTOR HAS AAV2 GENOMIC INVERTED TERMINAL REPEATS (ITR) AND ENCODES A HUMAN B-DOMAIN-DELETED BLOOD COAGULATION FACTOR VIII (HF8, FACTOR VIII, FVIII) UNDER THE CONTROL OF A MODIFIED TRANSTHYRETIN (TTRM) PROMOTER.
rovoctocogene durparvovec [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

ROVOCTOCOGENE DURPARVOVEC

Synonyms and Mappings

Resources