SIMARAVIBART

UNII:	5C4T4W973X
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	SIMARAVIBART
GSRS Full Record:	5C4T4W973X i

2657609-23-7
Immunoglobulin G1 [242-alanine,243-alanine,337-glycine,436-leucine,442-serine], anti-(severe acute respiratory syndrome coronavirus 2 spike glycoprotein receptor-binding domain) (human monoclonal MAD0004J08 γ1-chain), disulfide with human monoclonal MAD0004J08 κ-chain, dimer
MAD 0004J08 [WHO-DD]
MAD-0004J08
Simaravibart
gamma1 heavy chain Homo sapiens (1-455) [VH (Homo sapiens IGHV1-69*08 (95.9%) -(IGHD) -IGHJ4*01 (93.3%), CDR-IMGT [8.8.18] (26-33.51-58.97-114)) (1-125)-Homo sapiens IGHG1*03, G1m3, nG1m1, G1v14-49 CH2 A1.3, A1.2, G114, G1v24 CH3 L107, S114 (CH1 R120 (222) (126-223), hinge 1-15 (224-238), CH2 L1.3>A (242), L1.2>A (243), P114>G (337) (239-348), CH3 E12 (364), M14 (366), M107>L (436), N114>S (349-453), CHS (454-455)) (126-455)], (228-210')-disulfide with kappa light chain Homo sapiens (1'-210') [V-KAPPA (Homo sapiens IGKV3-11*01(97.8%)-IGKJ4*01 (100%), CDR-IMGT [6.3.5] (27-32.50-52.89-93)) (1'-103') -Homo sapiens IGKC*01 (100%), Km3, A45.1 (149),V101 (187) (104'-210')]; dimer (234-234'':237-237'')-Bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa
simaravibart (immunoglobulin G1-kappa, anti-[Homo sapiens severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein, receptor binding domain (RBD)], Homo sapiens monoclonal antibody)
simaravibart [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

SIMARAVIBART

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