BOSEROLIMAB

UNII:	576SCZ7V2P
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	BOSEROLIMAB
GSRS Full Record:	576SCZ7V2P i

2444297-08-7
BOSEROLIMAB [USAN]
Boserolimab
IMMUNOGLOBULIN G1, ANTI-(HUMAN CD27 ANTIGEN) (HUMAN-MUS MUSCULUS CLONE 131A6 .GAMMA.1-CHAIN)
MK 5890 [WHO-DD]
MK-5890
MK5890
boserolimab [INN]
gamma1 heavy chain (1-446) [VH (Homo sapiens IGHV1-2*02 (79.6%) -(IGHD) -IGHJ6*01 (100%), CDR-IMGT [8.8.9] (26- 33.51-58.97-105)) (1-116) -Homo sapiens IGHG1*01, G1m17,1 (CH1 K120 (213) (117-214), hinge 1-15 (215-229), CH2 (230- 339), CH3 D12 (355), L14 (357) (340-444), CHS (445-446)) (117-446)], (219-213')-disulfide with kappa light chain (1'-213') [V-KAPPA Musmus/Homsap (Mus musculus IGKV4-59*01 (80.9%) -IGKJ4*01 (91.7%) S120>Q (104)/Homo sapiens IGKV3-11*01 (80.0%) -IGKJ2*02 (100%), CDR-IMGT [5.3.9] (27- 31.49-51.88-96)) (1'-106') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (152), V101 (190) (107'-213')]; dimer (225-225'':228-228'')- bisdisulfide, produced in Chinese hamster ovary (CHO) cells, derived from the cell line CHO-K1, glycoform alfa
immunoglobulin G1-kappa, anti-[Homo sapiens CD27 (TNFRSF7, tumor necrosis factor receptor (TNFR) superfamily member 7)]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

BOSEROLIMAB

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