PEMIVIBART

UNII:	557S3L3FAP
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	PEMIVIBART
GSRS Full Record:	557S3L3FAP i

2858673-18-2
Immunoglobulin G1 [435-leucine,441-alanine], anti-(severe acute respiratory syndrome coronavirus 2 spike glycoprotein receptor-binding domain) (human monoclonal VYD222 γ1-chain), disulfide with human monoclonal VYD222 λ2-chain, dimer
Immunoglobulin G1-lambda2, anti-[severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein, receptor binding domain (RBD)], Homo sapiens monoclonal antibody; gamma1 heavy chain Homo sapiens (1-454) [VH (Homo sapiens IGHV3-21*07 (88.8%) -(IGHD) -IGHJ4*01 (92.9%), CDR-IMGT [8.8.17] (26-33.51-58.97-113)) (1-124) -Homo sapiens IGHG1*03, G1m3, nG1m1 CH1 R120, CH3 E12, M14, G1v78 L107, A114 (CH1 R120 (221) (125-222), hinge 1-15 (223-237), CH2 (238-347), CH3 E12 (363), M14 (365), M107>L (435), N114>A (441) (348-452), CHS (453-454)) (125-454)], (227-217')-disulfide with lambda2 light chain Homo sapiens (1'-218') [VLAMBDA (Homo sapiens IGLV1-40*01 (95.9%) -IGLJ1*01 (91.7%), CDR-IMGT [9.3.12] (26'-34'.52'-54'.91'-102')) (1'-112') -Homo sapiens IGLC2*01 (100%) (113'-218')]; dimer (233-233'':236-236'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1, glycoform alfa
PEMIVIBART [USAN]
Pemivibart
Pemivibart [WHO-DD]
gamma1 heavy chain Homo sapiens (1-454) [VH (Homo sapiens IGHV3-21*07 (88.8%) -(IGHD) -IGHJ4*01 (92.9%), CDR-IMGT [8.8.17] (26-33.51-58.97-113)) (1-124) -Homo sapiens IGHG1*03, G1m3, nG1m1 CH1 R120, CH3 E12, M14, G1v78 L107, A114 (CH1 R120 (221) (125-222), hinge 1-15 (223-237), CH2 (238-347), CH3 E12 (363), M14 (365), M107>L (435), N114>A (441) (348-452), CHS (453-454)) (125-454)], (227-217')-disulfide with lambda2 light chain Homo sapiens (1'-218') [V-LAMBDA (Homo sapiens IGLV1-40*01 (93.8%) -IGLJ1*01 (91.7%), CDR-IMGT [9.3.12] (26'-34'.52'-54'.91'-102')) (1'-112') -Homo sapiens IGLC2*01 (100%) (113'-218')]; dimer (233-233'':236-236'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1, glycoform alfa
immunoglobulin G1-lambda2, anti-[severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein, receptor binding domain (RBD)], Homo sapiens monoclonal antibody
pemivibart [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

PEMIVIBART

Synonyms and Mappings

Resources