VELUCOVACAP

UNII:	54HU9J47SF
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	VELUCOVACAP
GSRS Full Record:	54HU9J47SF i

2856375-51-2
Fibronectin-binding protein (recombinant Streptococcus dysgalactiae catcher moiety-containing) fusion protein with peptide linker (GSGS) fusion protein with viral spike glycoprotein (severe acute respiratory syndrome coronavirus 2 receptor-binding domain) fusion protein with peptide (synthetic linker-C-tag), henhexacontamer, (9′→32)-amide with peptide [9-aspartic acid] (synthetic split protein tag) fusion protein with linker (GSGTAGGGSGS) fusion protein with viral coat protein (bacteriophage AP205), octacontahectamer
N-L-glycyl-split protein tag peptide (2-15) fused via the peptide linker16GSGTAGGGSGS26 to Acinetobacter phage AP205 coat protein fragment (Met1 >del, 2-131, 27-156 in the current sequence), produced in Escherichia coli, conjugated via isopeptide bond (formed by the reaction between N9 and K32 with associated loss of one amino group) to N-L -glycyl-catcher peptide fragment (2-114) derived from Streptococcus dysgalactiae fibronectin binding protein fused via peptide linker 115GSGS118to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike glycoprotein (S glycoprotein) receptor binding domain (RBD) fragment (GenBank ID: QIA20044.1;306-578, 119-391 in the current sequence) fused via peptide linker 392GSGS395to a 396EPEA399C-terminal tag peptide, produced in Drosophila melanogaster S2 cells, glycoform alfa. The Acinetobacter phage AP205 coat protein-containing monomers self-assemble into a virus-like particle (VLP) consisting of 180 subunits of which approximately 61 surface exposed copies spontaneously conjugate with the RBD-containing recombinant fusion protein when mixed together
Velucovacap
velucovacap [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

VELUCOVACAP

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