SURZEBICLIMAB

UNII:	53YMC3A1CU
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	SURZEBICLIMAB
GSRS Full Record:	53YMC3A1CU i

2342597-90-2
ANTI-TIM-3 MONOCLONAL ANTIBODY BGB-A425
BGB-A425
BGBA425
Immunoglobulin G1 [235-proline,236-alanine,237-alanine,de-239-glycine,331-alanine], anti-(human hepatitis A virus cellular receptor 2) (human-Mus musculus monoclonal BGB-A425 γ1-chain), disulfide with human-Mus musculus monoclonal BGB-A425 κ-chain, dimer
Immunoglobulin G1-kappa, anti-[Homo sapiens HAVCR2 (hepatitis A virus cellular receptor 2, T-cell immunoglobulin mucin family member 3, Tim-3, TIM3, TIMD3, CD366)], monoclonal antibody; gamma1 heavy chain (1-448) [VH (Homo sapiens IGHV3-23*04 (93.8%) -(IGHD) -IGHJ4*01 (100%)) CDR-IMGT [8.7.13] (26-33.51-57.96-108) (1-119) -Homo sapiens IGHG1*01, G1m17,1, G1v4 CH2 A114 (CH1 K120 (217) (120-217), hinge 1-15 (218-232), linker (233-237), CH2 P114>A (330) (238-341), CH3 D12 (357), L14 (359) (342-446), CHS (447-448)) (120-448)], (222-218')-disulfide with kappa light chain (1’-218’) [V-KAPPA (Homo sapiens IGKV3-15*01 (84%) -IGKJ4*01 (100%)) CDR-IMGT [10.3.9] (27-36.54-56.93-101) (1'-111') -Homo sapiens IGKC*01 (100%) Km3 A45.1 (157), V101 (195) (112'-218')]; dimer (228-228'':231-231'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa
SURZEBICLIMAB [USAN]
Surzebiclimab
Surzebiclimab [WHO-DD]
surzebiclimab [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

SURZEBICLIMAB

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