AMLENETUG

UNII:	52V6AS6U0A
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	AMLENETUG
GSRS Full Record:	52V6AS6U0A i

2850367-41-6
AF-82422
AMLENETUG [USAN]
Amlenetug
H-gamma1 heavy chain Homo sapiens (1-445) [VH (Homo sapiens IGHV3-23*01 (90.8%) -(IGHD) -IGHJ4*01 (92.9%), CDR-IMGT [8.8.9] (26-33.51-58.97-105)) (1-116) -Homo sapiens IGHG1*03 (100%), G1m3, nG1m1 CH1 R120, CH3 E12, M14 (CH1 R120 (213) (117-214), hinge 1-15 (215-229), CH2 (230-339), CH3 E12 (355), M14 (357) (340-444), CHS K2>del (445)) (117-445)], (219-215')-disulfide with L-kappa light chain Homo sapiens (1'-215') [V-KAPPA(Homo sapiens IGKV3-20*01 (100%) -IGKJ1*01 (100%), CDR-IMGT [7.3.9](27'-33'.51'-53'.90'-98')) (1'-108') -Homo sapiens IGKC*01 (100%), Km3 A45.1(154'), V101 (192') (109'-215')]; dimer (225-225'':228-228'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1SV, lacking the glutamine synthetase (GS-KO) gene, glycoform alfa
Immunoglobulin G1 [de-C-terminal-lysine], anti-(human α-synuclein) (human monoclonal Lu AF82422 γ1-chain), disulfide with human monoclonal Lu AF82422 κ-chain, dimer
LU AF-82422
LU AF82422
LU AF82422 (HUMAN IGG1 MAB THAT RECOGNIZES ALL MAJOR SPECIES OF ALPHA-SYNUCLEIN)
LUAF-82422
LUAF82422
amlenetug [INN]
mmunoglobulin G1-kappa, anti-[Homo sapiens SNCA (synuclein alpha, PARK1, PARK4, Parkinson disease (autosomal dominant, Lewy body) 4, synuclein alpha (non A4 component of amyloid precursor))], Homo sapiens monoclonal antibody

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

AMLENETUG

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