TALQUETAMAB

UNII:	4W3KFI3TN3
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	TALQUETAMAB
GSRS Full Record:	4W3KFI3TN3 i

2226212-40-2
IMMUNOGLOBULIN G4-KAPPA/G4-LAMBDA, ANTI-(HOMO SAPIENS GPRC5D (G PROTEIN-COUPLED RECEPTOR CLASS C GROUP 5 MEMBER D)), AND ANTI-(HOMO SAPIENS CD3E (CD3 EPSILON, LEU-4)), HUMANIZED AND CHIMERIC MONOCLONAL ANTIBODY, BISPECIFIC
Immunoglobulin G4 [233-proline,239-alanine,240-alanine,410-leucine,414-lysine], anti-(human CD3 antigen) (human monoclonal JNJ-63483043 γ4-chain), disulfide with human monoclonal JNJ-63483043 λ-chain, (231→224′), (234→227′)-bis(disulfide) with immunoglobulin G4 [226-proline,232-alanine,233-alanine] anti-(human G protein-coupled receptor GPRC5D) (human monoclonal JNJ-64386972 γ4-chain) disulfide with human monoclonal JNJ-64386972 λ-chain
Immunoglobulin G4-kappa/G4-lambda, anti-[Homo sapiens GPRC5D (G protein-coupled receptor class C group 5 member D)], and anti-[Homo sapiens CD3E (CD3 epsilon, Leu-4)], humanized and chimeric monoclonal antibody; bispecific gamma4 heavy chain humanized anti-GPRC5D (1-445) [VH (Homo sapiens IGHV1-18*01 (89.8%) -(IGHD) -IGHJ4*01 (92.9%)) [8.8.11] (1-118) -Homo sapiens IGHG4*01 (CH1 (119-216), hinge 1-12 S10>P (226) (217-228), CH2 F1.3>A (232), L1.2>A (233) (229-338), CH3 (339-443), CHS (444-445)) (119-445)], (132-214')-disulfide with kappa light chain humanized antiGPRC5D (1'-214') [V-KAPPA (Homo sapiens IGKV1-17*02 (85.3%) -IGKJ2*01 (100%)) [6.3.9] (1'-107') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (153), V101 (191) (108'-214’)]; gamma4 heavy chain chimeric anti-CD3E (1-452) [VH (Mus musculus IGHV10-1*02 (89.8%)/Homo sapiens IGHV3-72*01 (88.0%) -(IGHD) -IGHJ6*01 (90.9%)) [8.10.16] (1-125) -Homo sapiens IGHG4*01 (CH1 (126-223), hinge 1-12 S10>P (233) (224-235), CH2 F1.3>A (239), L1.2>A (240) (236-345), CH3 F85.1>L (410), R88>K (414) (346-450), CHS (451-452)) (126-452)], (139-214')-disulfide with lambda light chain humanized anti-CD3E (1'-215') [V-LAMBDA (Homo sapiens IGLV7-43*01 (81.9%) -IGLJ3*02 (100%)) [9.3.9] (1'-109') -Homo sapiens IGLC2*01 (100%) (110'-215’)]; dimer (224-231'':227-234'')-bisdisulfide, produced in Chinese Hamster Ovary (CHO)-K1 cell line, glycoform alfa
JNJ-64407564
TALQUETAMAB [USAN]
TALVEY
Talquetamab
Talquetamab [MI]
Talquetamab [WHO-DD]
Talquetamab tgvs [WHO-DD]
Talquetamab-TGVS
talquetamab [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

TALQUETAMAB

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