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LINCLATAMIG

UNII:4NHP5YXY4Z
Type:INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:LINCLATAMIG
GSRS Full Record:
4NHP5YXY4Z
i

  • 2885203-43-8
  • H-gamma1 heavy chain anti-LY6G6D humanized, G1v84-1 VH E44, CH1 K86 (1-442) [VH E44 (Homo sapiens IGHV3-23*01 (77.6%) -(IGHD) -IGHJ2*01 (92.3%) R120>P (104), CDR-IMGT [8.8.5] (26-33.51-58.97-101)) (1-112) -Homo sapiens IGHG1*03v, G1m3>G1m17, nG1m1, CH1 K120, CH3 E12, M14, CH1 K86, G1v30 CH2 G84.4, G1v32 CH3 W22 (knob) (CH1 R120>K (209), S86>K (178) (113-210), hinge 1-15 (211-225), CH2 N84.4>G (292) (226-335), CH3 E12 (351), M14 (353), T22>W (361) (336-440), CHS (441-442)) (123-442)], (215-218')-disulfide with L-kappa light chain humanized, Kv84-1 VK K44, CK E22 (1'-218') [V-KAPPA K44 (Homo sapiens IGKV1-5*01 (89.8%) -IGKJ4*01 (100%), CDR-IMGT [6.3.13] (27'-32'.50'-52'.89'-101')) (1'-111') -Homo sapiens IGKC*01 (99.1%) V22>E (137), Km3 A45.1 (157), V101 (195) (112'-218')]
  • Immunoglobulin G1 [39-lysine,185-glutamic acid,299-glycine,368-serine,370-alanine,409-valine], anti-(human CD3 antigen ε-chain) (human-Mus musculus clone 38E4v1-MD1 γ1-chain) disulfide with [44-glutamic acid,138-lysine] human-Mus musculus clone 38E4v1-MD1 κ-chain, (228→221′),(231→224′)-bis(disulfide) with immunoglobulin G1 [39-glutamic acid,178-lysine,292-glycine,361-tryptophan] anti-(human lymphocyte antigen Ly6G6D) (human-Oryctolagus cuniculus clone 20A12.QNTv12 γ1-chain) disulfide with [38-lysine,137-glutamic acid] human-Oryctolagus cuniculus clone 20A12.QNTv12 κ-chain
  • Linclatamig
  • immunoglobulin G1-kappa, anti-[Homo sapiens LY6G6D (lymphocyte antigen 6 family member G6D, G6D, LY6-D, MEGT1, NG25)] and anti-[Homo sapiens CD3E (CD3 epsilon, Leu-4)], humanized monoclonal antibody, bispecific
  • linclatamig [INN]




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