ARCOTATUG

UNII:	4KP47V43RH
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	ARCOTATUG
GSRS Full Record:	4KP47V43RH i

3031170-61-0
Arcotatug
H-gamma1 heavy chain Homo sapiens (1-452) [VH (Homo sapiens IGHV3-23*01 (94.8%) -(IGHD) -IGHJ5*01 (100%), CDR-IMGT [8.8.15] (26-33.51-58.97-111)) (1-122) -Homo sapiens IGHG1*01 (100%) G1m17,1 CH1 K120, CH3 D12, L14 (CH1 K120 (219) (123-220), hinge 1-15 (221-235), CH2 (236-345), CH3 D12 (361), L14 (363) (346-450), CHS (451-452)) (123-452)], (225-214')-disulfide with L-kappa light chain Homo sapiens (1'-214') [V-KAPPA (Homo sapiens IGKV1-5*03 (100%) -IGKJ2*01 (100%), CDR-IMGT [6.3.9] (27'-32'.50'-52'.89'-97')) (1'-107') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (153'), V101 (191')) (108'-214')]; dimer (231-231'':234-234'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1SV lacking the glutamine synthetase (GS-KO) gene, glycoform alfa
Immunoglobulin G1, anti-(human claudin CLDN18.2) (human monoclonal HB37A6 γ1-chain), disulfide with human monoclonal HB37A6 κ-chain, dimer
arcotatug [INN]
immunoglobulin G1-kappa, anti-[Homo sapiens CLDN18 (claudin 18, claudin-18, surfactant associated protein J, SFTPJ) isoform 2], Homo sapiens monoclonal antibody (arcotatug)

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

ARCOTATUG

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