LUVOMERAN

UNII:	4HS3TYX8MY
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	LUVOMERAN
GSRS Full Record:	4HS3TYX8MY i

2845125-98-4
CX-025984
LUVOMERAN [USAN]
Luvomeran
Messenger RNA encoding human cystic fibrosis transmembrane conductance regulator (hCFTR)
RNA (recombinant 5′-(m7G-(5′→5′)-ppp-Gm)-capped all uridine→N1-methylpseudouridine-substituted human cystic fibrosis transmembrane conductance regulator protein plus 5′-and 3′-untranslated flanking region-containing poly(A)-tailed messenger CX-025984), inner salt
VX-522-mRNA
VXc-522
luvomeran [INN]
mRNA-3692 RNA
messenger RNA (mRNA), 5' capped, encoding codonoptimised human cystic fibrosis transmembrane conductance regulator (hCFTR; channel conductancecontrolling ATPase, cAMP-dependent chloride channel, ATP-binding cassette sub-family C member 7), flanked by 5' and 3' untranslated regions based on the Mus musculus histone H1.5 gene and the human haemoglobin subunit alpha (HBA1) gene, followed by a 3' polyadenylation (polyA) tail (containing a 100-nucleotide polyA sequence, a 5-nucleotide XbaI scar and a 20-nucleotide polyA sequence ending with an inverted dT); contains N1-methylpseudouridine instead of uridine (all-U>m1Ψ)

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

LUVOMERAN

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