PELUNTAMIG

UNII:	4A6ZWS8R8E
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	PELUNTAMIG
GSRS Full Record:	4A6ZWS8R8E i

2928515-21-1
Bispecific Antibody against DLL3 and CD47
H-gamma1 heavy chain anti-CD47 (1-444) [VH (Homo sapiens IGHV1-46*01 (88.7%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.7] (26-33.51-58.97-103)) (1-114) -Homo sapiens IGHG1*01 G1m17,1 CH1 K120, CH3 D12, L14, G1v74 CH3 C10, G1v32 CH3 W22 (knob) (CH1 K120 (211) (115-212), hinge 1-15 (213-227), CH2 (228-337), CH3 S10>C (351), D12 (353), L14 (355), T22>W (363) (338-442), CHS (443-444)) (115-444)], (217-214')- disulfide with common L-kappa light chain (1'-214') [V-KAPPA (Homo sapiens IGKV3-20*01 (84.4%) -IGKJ1*01 (91.7%), CDR-IMGT [6.3.9] (27'-32'.50'-52'.89'-97')) (1'-107') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (153'), V101 (191')) (108'-214')];
Immunoglobulin G1 [350-cysteine,367-serine,369-alanine,408-valine], anti-(human notch ligand DLL3) (human-Mus musculus monoclonal PT217 γ1-chain), disulfide with human-Mus musculus monoclonal PT217 κ-chain, (227→223′),(230→226′),(350→351′)-tris(disulfide) with immunoglobulin G1 [351-cysteine,363-tryptophan] anti-(human CD47 antigen) (human-Mus musculus monoclonal PT217 γ1-chain) disulfide with human-Mus musculus monoclonal PT217 κ-chain
PELUNTAMIG [USAN]
PT-217
PT217
Peluntamig
immunoglobulin H-gamma1_L-kappa, anti-[Homo sapiens CD47 (CD47 molecule, integrin associated protein, IAP, MER6, OA3) and anti-[Homo sapiens DLL3 (delta-like ligand 3, delta like canonical Notch ligand 3)], bispecific;
peluntamig [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

PELUNTAMIG

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