ROLISTOBART

UNII:	49E3KB7L5M
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	ROLISTOBART
GSRS Full Record:	49E3KB7L5M i

2723442-10-0
Immunoglobulin G4 [230-proline], anti-(human leukocyte Ig-like receptor B4) (human-Mus musculus monoclonal A197U γ-4 chain), disulfide with human-Mus musculus monoclonal A197U κ-chain, dimer
Immunoglobulin G4-kappa, anti-[Homo sapiens LILRB4 (leukocyte immunoglobulin like receptor B4, ILT3, LIR-5, CD85k)], humanized monoclonal antibody (gamma4 heavy chain humanized (1-449) [VH (Homo sapiens IGHV3-7*01 (86.7%) -(IGHD) -IGHJ4*01(100%), CDR-IMGT [8.8.15] (26-33.51-58.97-111)) (1-122) -Homo sapiens IGHG4*01, nG4m(a) CH2 L92, G4v5 h P10 (CH1 (123-220), hinge 1-12 S10>P (230)(221-232), CH2 L92 (311) (233-342), CH3 (343-447), CHS (448-449)) (123-449)], (136-218')-disulfide with kappa light chain humanized (1'-218') [V-KAPPA (Homo sapiens IGKV1-9*03 (81.6%) -IGKJ2*01(100%), CDR-IMGT [10.3.9] (27-36.54-56.93-101)) (1'-111') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (157), V101 (195) (112'-218')]; dimer (228-228'':231-231'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa)
Rolistobart
rolistobart [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

ROLISTOBART

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