DISITAMAB

UNII:	474FJM6Y9C
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	DISITAMAB
GSRS Full Record:	474FJM6Y9C i

2185868-98-6
DISITAMAB [USAN]
Disitamab
Immunoglobulin G1, anti-(human tyrosine kinase receptor ErbB2) (human-Mus musculus monoclonal RC48-0 γ1-chain), disulfide with human-Mus musculus monoclonal RC48-0 κ-chain, dimer
Immunoglobulin G1-kappa, anti-[Homo sapiens ERBB2 (epidermal growth factor receptor 2, receptor tyrosine-protein kinase erbB-2, EGFR2, HER2, HER-2, p185c-erbB2, NEU, CD340)], humanized monoclonal antibody; gamma1 heavy chain humanized (1-445) [VH (Homo sapiens IGHV1-69-2*01 (83.5%) -(IGHD) -IGHJ1*01 (92.9%)) [8.8.8] (1-115) -Homo sapiens IGHG1*03v, G1m3>G1m17, nG1m1 (CH1 R120>K (212) (116-213), hinge (214-228), CH2 (229-338), CH3 E12 (354), M14 (357) (339-443), CHS (444-445)) (116-445)] (218-212')-disulfide with kappa light chain humanized (1'-212') [V-KAPPA (Homo sapiens IGKV1-39*01 (83.3%) IGKJ4*01 (100%))[6.3.7] (1'-105') -Homo sapiens IGKC*01 (100%) Km3 A45.1 (151), V101 (189) (106'-212')]; dimer (224-224'':227-227'')-bisdisulfide
RC-48
RC48
disitamab [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

DISITAMAB

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