EFDELIKOFUSP ALFA

UNII:	3Y7ANB3DKG
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	EFDELIKOFUSP ALFA
GSRS Full Record:	3Y7ANB3DKG i

2922216-49-5
1-208-CD80 antigen (human) fusion protein with peptide linker (GS(GGGGS)3) fusion protein with immunoglobulin G4 (recombinant human γ4-chain hinge-CH2-CH3 fragment) fusion protein with peptide linker (GGGGS) fusion protein with interleukin 2 [38-alanine,42-alanine] (human), dimer
Bi-specific fragment crystallizable region (Fc) fusion protein containing cluster of differentiation 80 ectodomain as an N-terminal moiety and interleukin-2 variant as a C-terminal moiety conjugated with human immunoglobulin G4 Fc
Efdelikofusp Alfa
GI 101 [WHO-DD]
GI-101
efdelikofusp alfa [INN]
human T-lymphocyte activation antigen CD80 (activation B7-1 antigen, CTLA-4 counter-receptor B7.1, CD80) extracellular domain containing fragment (1-208 in the current sequence) fused via peptide linker 209GSGGGGSGGGGSGGGGS225 to an Fc fragment of human immunoglobulin G4 (226-454) [Homo sapiens IGHG4*01, hinge ins226>A, S236>P (226-238), CH2 F242>A, L243>A, T258>Q (239-348), CH3 M436>L (349-453), CHS K455>del (454)] fused via peptide/ linker 455GGGGS459 to human interleukin-2 (IL-2, T-cell growth factor (TCGF)) (1-133, 460-592 in the current sequence), variant (R38>A497, F42>A501), dimer (234-234', 237-237')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

EFDELIKOFUSP ALFA

Synonyms and Mappings

Resources