ENEKINRAGENE INZADENOVEC

UNII:	3KJ43QLJ8F
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	ENEKINRAGENE INZADENOVEC
GSRS Full Record:	3KJ43QLJ8F i

2618581-50-1
ENEKINRAGENE INZADENOVEC [USAN]
Enekinragene Inzadenovec
FX-201
FX201
GQ-203
GQ203
Humantakinogene hadenovec
PCRX-201
enekinragene inzadenovec [INN]
recombinant, non-replicating adenovirus type 5 (Ad5) vector encoding codon-optimised human interleukin 1 receptor antagonist (IL-1Ra) under the control of an engineered nuclear factor kappa B (NF-κB) inducible promoter composed of five conserved NF-κB binding motif repeats fused to a proximal promoter region of the human endothelial leukocyte adhesion molecule (ELAM) gene (NF-κB5-ELAM), and terminated by a simian virus 40 (SV40) polyadenylation sequence. The vector genome is flanked by human Ad5 inverted terminal repeats (ITRs) and the bulk of the adenovirus genome has been replaced by a non-coding human hypoxanthine phosphoribosyltransferase (HPRT) stuffer sequence and by a human non-coding cosmid insert containing the polymorphic marker DXS455

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

ENEKINRAGENE INZADENOVEC

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