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VINTESOMERAN

UNII:3E9P89C6JX
Type:INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:VINTESOMERAN
GSRS Full Record:
3E9P89C6JX
i

  • 2923391-66-4
  • CX-040631
  • CX-040631 (COVID-19 Omicron variant XBB.1.16)
  • CX-040631 Omicron (XBB.1.16)
  • RNA (recombinant 5′-(m7G-(5′→5′)-ppp-Gm)-capped all uridine→N1-methylpseudouridine-substituted severe acute respiratory syndrome coronavirus 2 pre-fusion spike glycoprotein [982-proline,983-proline] XBB.1.16 variant plus 5′- and 3′-untranslated flanking region-containing poly(A)-tailed messenger CX-040631), inner salt
  • Vintesomeran
  • messenger RNA (mRNA), 5'-capped, encoding a full-length, codon-optimised pre-fusion stabilised conformation variant (K982P and V983P) of the SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) spike (S)glycoprotein (Omicron variant XBB.1.16; based upon GISAID:EPI_ISL_16835403) further optimized by two additional stop codons, flanked by an artificial 5' untranslated region (UTR) and a 3' UTR derived from the human alpha globin gene (HBA1) modified to contain an identification and ratio (IDR) sequence to enable identification and relative ratio determination of individual RNA components in a multivalent mRNA vaccine, and terminated by a 3' polyadenylation (polyA) tail; contains N<sup>1</sup>-methylpseudouridine instead of uridine (all-U>m <sup>1</sup>Ψ)
  • vintesomeran [INN]




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