LEREPMERAN

UNII:	3DMH5L9FB8
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	LEREPMERAN
GSRS Full Record:	3DMH5L9FB8 i

2924731-63-3
CX-032064
Lerepmeran
RNA (recombinant 5′-(m7G-(5′→5′)-ppp-Gm)-capped all uridine→N1-methylpseudouridine-substituted 5′-untranslated region plus human propionyl-CoA carboxylase α subunit plus 3′-untranslated region-containing microRNA-142 binding sites plus poly(A)-tailed messenger CX-032064), inner salt
lerepmeran [INN]
messenger RNA (mRNA), 5'(m7G-(5'→5')-ppp-Gm)-capped, encoding codon-optimised human propionyl-CoA carboxylase subunit alpha (PCCA), flanked by 5' and 3' untranslated regions (UTRs), followed by a 3' polyadenylation (polyA) tail and concluded by a 5-nucleotide XbaI scar. The 3' UTR contains three microRNA-142 (miR-142) binding sites. Contains N1-methylpseudouridine instead of uridine (all-U>m1Ψ)

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UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

LEREPMERAN

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