ZADOPRUBART

UNII:	39T86A9MVJ
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	ZADOPRUBART
GSRS Full Record:	39T86A9MVJ i

2904575-77-3
H-gamma4 heavy chain humanized (1-451) [VH (Homo sapiens IGHV1-69*08 (80.6%) -(IGHD) -IGHJ6*05 (92.3%) A127>S (123), CDR-IMGT [8.8.17] (26-33.51-58.97-113)) (1-124) -Homo sapiens IGHG4*01, nG4m(a) CH2 L92, G4v5 h P10(CH1 (125-222), hinge 1-12 S10>P (232) (223-234), CH2 L92 (313) (235-344), CH3 (345-449), CHS (450-451)) (125-451)], (138-214')-disulfide with L-kappa light chain humanized (1'-214') [V-KAPPA (Homo sapiens IGKV1-12*01 (86.4%) -IGKJ4*01 (100%), CDR-IMGT [6.3.9] (27'-32'.50'-52'.89'-97')) (1'-107') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (153'), V101 (191')) (108'-214')]; dimer (230-230'':233-233'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1, glycoform alfa
Immunoglobulin G4, anti-(human/Macaca fascicularis protein BTLA (B-and T-lymphocyte attenuator)) (human-Mus musculus monoclonal ANB032 γ4-chain), disulfide with human-Mus musculus monoclonal ANB032 κ-chain, dimer
Zadoprubart
immunoglobulin G4-kappa, anti-[Homo sapiens BTLA (B and T lymphocyte attenuator, BTLA1, CD272)], humanized monoclonal antibody
zadoprubart [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

ZADOPRUBART

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