EVRULEUCEL

UNII:	35C6UF9WLP
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	EVRULEUCEL
GSRS Full Record:	35C6UF9WLP i

ATA-188
ATA188
Allogeneic cytotoxic T lymphocytes that are derived from peripheral blood mononuclear cells (PBMCs) from healthy Epstein-Barr virus (EBV) seropositive donors and have been transduced with a viral vector expressing latent membrane protein 1 (LMP1), LMP2, and EBV nuclear antigen 1 (EBNA1). PBMCs are thawed and a portion of these cells are incubated with a replication-deficient adenovirus encoding a transgene that expresses an EBV polyepitope protein to produce antigen-presenting cells (APCs). These APCs are irradiated to arrest their replication and then added to the remaining PBMCs to stimulate and induce the expansion of EBV-specific T-cells that can target EBV transformed B lymphocytes
EVRULEUCEL [USAN]
Evruleucel
Evruleucel [WHO-DD]
evruleucel [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

EVRULEUCEL

Synonyms and Mappings

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