VIMZIPRUBART

UNII:	34257Z97JJ
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	VIMZIPRUBART
GSRS Full Record:	34257Z97JJ i

3084196-24-4
H-gamma1 heavy chain Homo sapiens (1-448) [VH (Homo sapiens IGHV3-23*04 (88.8%) -(IGHD) -IGHJ5*01 (90.9%) L123>Q (113), CDRIMGT[8.8.11] (26-33.51-58.97-107)) (1-118) -Homo sapiens IGHG1*01,G1m17,1 CH1 K120, CH3 D12, L14, 6-G1v14 CH2 A1.3, A1.2, 9-G1v21 CH2 Y15.1, T16, E18 (CH1 K120 (215) (119-216), hinge 1-15 (217-231),CH2 L1.3>A (235), L1.2>A (236), M15.1>Y (253), S16>T (255), T18>E(257) (232-341), CH3 D12 (357), L14 (359) (342-446), CHS (447-448))(119-448)], (221-214')-disulfide with L-kappa light chain Homo sapiens (1'-214') [V-KAPPA (Homo sapiens IGKV1-17*01 (95.8%) -IGKJ3*01 (100%),CDR-IMGT [6.3.9] (27'-32'.50'-52'.89'-97')) (1'-107') -Homo sapiens IGKC*01 (100%) Km3 A45.1, V101 (C-KAPPA A45.1 (153'), V101 (191'))(108'-214')]; dimer (227-227'':230-230'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1, glycoform alfa
Immunoglobulin G1 [235-alanine,236-alanine,253-tyrosine,255-threonine,257-glutamic acid], anti-(human OX40 ligand) (human-Mus musculus monoclonal AGP990 γ1-chain), disulfide with human-Mus musculus monoclonal AGP990 κ-chain, dimer
Immunoglobulin G1-kappa, anti-[Homo sapiens TNFSF4 (TNF superfamily member 4, tumor necrosis factor superfamily member 4, OX40 ligand, OX40L, TAX transcriptionally-activated glycoprotein 1, TXGP1, gp34, CD252)], Homo sapiens monoclonal antibody
Vimziprubart
vimziprubart [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

VIMZIPRUBART

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