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TOVESANGENE PARVEC

UNII:2XJ94NG3WX
Type:INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:TOVESANGENE PARVEC
GSRS Full Record:

  • 3064917-67-2
  • JAG-201
  • Tovesangene Parvec
  • recombinant non-replicating adeno-associated virus serotype 9 (rAAV9) vector encoding a miniaturised version of human SHANK3 (SH3 and multiple ankyrin repeat domains 3, proline-rich synapse-associated protein 2 (ProSAP2); corresponding to amino acids 537-782, 1347-1806 of the full-length SHANK3 protein, M1>added) preceded by a Kozak sequence with expression under control of the human synapsin I promoter, a Woodchuck hepatitis virus post-transcriptional regulatory element (WPRE) and a human growth hormone (hGH) polyadenylation signal; flanked by AAV2 inverted terminal repeats (ITRs)
  • tovesangene parvec [INN]



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