SABIRNETUG

UNII:	2U1A25MKP9
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	SABIRNETUG
GSRS Full Record:	2U1A25MKP9 i

2747959-38-0
ACU-193
ACU193
Immunoglobulin G2 [264-histidine,305-valine,326-alanine,327-proline], anti-(human Aβ oligomer) (human-Mus musculus monoclonal ACU193 g2-chain), disulfide with human-Mus musculus monoclonal ACU193 k-chain, dimer
SABIRNETUG [USAN]
Sabirnetug
immunoglobulin G2-kappa, anti-[Homo sapiens APP (amyloid beta A4 precursor protein) Abeta42 and Abeta40 soluble non-fibrillar oligomers], humanized monoclonal antibody; gamma2 heavy chain humanized (1-443) [VH (Homo sapiens IGHV3-48*01 (92.9%) -(IGHD) -IGHJ4*01 (92.9%), CDR-IMGT [8.8.10] (26-33.51-58.97-106)) (1-117) -Homo sapiens IGHG2*01, G2m.. CH2 V45.1 (CH1 (118-215), hinge 1-12 (216-227), CH2 V45.1 (278) (228-336), CH3 (337-441), CHS (442-443)) (118-443)], (131-219')-disulfide with kappa light chain humanized (1'-219') [V-KAPPA (Homo sapiens IGKV2-28*01 (89.5%) -IGKJ2*03 (100%), CDR-IMGT [11.3.9] (27-37.55-57.94-102)) (1'-112') -Homo sapiens IGKC*01, Km3 A45.1 (158), V101 (196) (113'-219')]; dimer (219-219'':220-220'':223-223'':226-226'')-tetrakisdisulfide, produced in Chinese hamster ovary (CHO) cells, glycoform alfa
sabirnetug [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

SABIRNETUG

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