NALOTIMAGENE CARMALEUCEL

UNII:	2SS05WO6EV
Formula:
Preferred Substance Name:	NALOTIMAGENE CARMALEUCEL
GSRS Full Record:	2SS05WO6EV i

HSV-TK
HUMAN CULTURE EXPANDED ACTIVATED ALLOGENEIC T CELLS FOR ADJUNCTIVE IMMUNOTHERAPY. CELLS ARE DERIVED FROM THE HAEMATOPOIETIC STEM CELL (HSC) DONOR AND ARE GENETICALLY MODIFIED EX VIVO WITH A NON-REPLICATIVE SFCMM-3 GAMMA- RETROVIRAL VECTOR DERIVED FROM MOLONEY MURINE LEUKEMIA VIRUS (MO-MULV), ENCODING FOR A TRUNCATED FORM OF THE HUMAN LOW AFFINITY NERVE GROWTH FACTOR RECEPTOR (?LNGFR) AND THE HERPES SIMPLEX VIRUS THYMIDINE KINASE (HSV-TK MUT2). CELLS CONTAIN A SUICIDE GENE IN CASE OF GRAFT VERSUS HOST DISEASE DEVELOPMENT
NALOTIMAGENE CARMALEUCEL [INN]
NALOTIMAGENE CARMALEUCEL [USAN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

NALOTIMAGENE CARMALEUCEL

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