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INSULIN LUDEFEN

UNII:2S3BP2LSQ2
Type:INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:INSULIN LUDEFEN
GSRS Full Record:

  • 2975655-22-0
  • (1<sup>A</sup>-21<sup>A</sup>),(1<sup>B</sup>-29<sup>B</sup>)-Insulin (human), 14<sup>A</sup>-L-glutamic acid-16<sup>B</sup>-L-histidine-25<sup>B</sup>-L-histidine-29<sup>B</sup>-[N<sup>6</sup>-[N-(21-carboxy-1-oxoheneicosyl)-L-γ-glutamyl-2-[2-(2-aminoethoxy)ethoxy]acetyl-2-[2-(2-aminoethoxy)ethoxy]acetyl-2-[2-(2-aminoethoxy)ethoxy]acetyl-2-[2-(2-aminoethoxy)ethoxy]acetyl-2-[2-(2-aminoethoxy)ethoxy]acetyl-2-[2-(2-aminoethoxy)ethoxy]acetyl-2-[2-(2-aminoethoxy)ethoxy]acetyl-2-[2-(2-aminoethoxy)ethoxy]acetyl-2-[2-(2-aminoethoxy)ethoxy]acetyl-2-[2-(2-aminoethoxy)ethoxy]acetyl-2-[2-(2-aminoethoxy)ethoxy]acetyl-2-[2-(2-aminoethoxy)ethoxy]acetyl]-L-lysine]-
  • Insulin Ludefen
  • human insulin (Uniprot: P01308) B chain, variant (Y<sup>B16</sup>>H, F<sup>B25</sup>>H, T<sup>B30</sup>>del)disulfide bridged to human insulin A chain, variant (Y<sup>A14</sup>>E) modified at the C-terminus of the B chain with N<sup>6.B29</sup> -[N-(21-carboxyhenicosanoyl)-L-γ-glutamyldodecakis{[2-(2-aminoethoxy)ethoxy]acetyl}], produced in Escherichia coli strain W3110, not glycosylated N<sup>6.B29</sup>-[N-(21-carboxyhenicosanoyl)- L-γ-glutamyldodecakis{[2-(2-aminoethoxy)ethoxy]acetyl}][Y<sup>A14</sup> >E, Y<sup>B16</sup>>H, F<sup>B25</sup> >H]-B30-des- L-threonine-insulin (human)
  • insulin ludefen [INN]



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