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OPOLIMOGENE CAPMILISBAC

UNII:2O95SM11L5
Type:INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:OPOLIMOGENE CAPMILISBAC
GSRS Full Record:
2O95SM11L5
i

  • ADU-741
  • JNJ-64041809
  • OPOLIMOGENE CAPMILISBAC [USAN]
  • THE N-TERMINAL 100 AMINO ACIDS OF THE LM ACTA (ACTIN-ASSEMBLY INDUCING PROTEIN PRECURSOR) PROTEIN (ACTAN100), 5 TANDEM COPIES OF A 21 AMINO ACID FRAGMENT OF HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR VARIANT III (EGFRVIII) AND HUMAN PROTEIN SSX2 (SYNOVIAL SARCOMA, X BREAKPOINT 2, ALSO KNOWN AS CANCER/TESTIS ANTIGEN 5.2 (CT5.2), TUMOR ANTIGEN HOMMEL-40), UNDER THE CONTROL OF THE LM ACTA PROMOTER, AND CONTAINED WITHIN AN EXPRESSION CASSETTE OF 1434 BP INSERTED AT THE ACTA LOCUS
  • THE N-TERMINAL 100 AMINO ACIDS OF THE LM ACTA PROTEIN (ACTAN100), 5 TANDEM COPIES OF A 21 AMINO ACID FRAGMENT OF HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR VARIANT III (EGFRVIII) AND AMINO ACIDS 11-234 OF HUMAN HOMEOBOX PROTEIN NKX-3.1 (NKX3-1) PLUS AMINO ACIDS 1-20, 44- 138 AND 169-750 OF HUMAN GLUTAMATE CARBOXYPEPTIDASE 2 (ALSO KNOWN AS FOLATE HYDROLASE 1 (FOLH1), PROSTATE-SPECIFIC MEMBRANE ANTIGEN (PSMA)), UNDER THE CONTROL THE LM ACTA PROMOTER, AND CONTAINED WITHIN AN EXPRESSION CASSETTE OF 4984 BP AT THE TRNAARG LOCUS
  • THE N-TERMINAL 100 AMINO ACIDS OF THE LM ACTA PROTEIN (ACTAN100), 5 TANDEM COPIES OF A 21 AMINO ACID FRAGMENT OF HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR VARIANT III (EGFRVIII) AND AMINO ACIDS 33-386 OF HUMAN PROSTATIC ACID PHOSPHATASE (PAP), UNDER THE CONTROL THE LM ACTA PROMOTER, AND CONTAINED WITHIN AN EXPRESSION CASSETTE OF 2057 BP INSERTED AT THE INLB (INTERNALIN B) LOCUS
  • opolimogene capmilisbac [INN]




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