AZAMIDUGENE AUTOTEMCEL VECTOR

UNII:	2CX3CU3LQY
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	AZAMIDUGENE AUTOTEMCEL VECTOR
GSRS Full Record:	2CX3CU3LQY i

SELF-INACTIVATING LENTIVIRAL VECTOR EXPRESSING HUMAN ALPHA-L-IDURONIDASE (IDUA) UNDER THE CONTROL OF A HUMAN PHOSPHOGLYCERATE KINASE (PGK)PROMOTER THE CONSTRUCT IS FLANKED BY 5' AND 3' LONG TERMINAL REPEATS (LTRS) AND ALSO CONTAINS A HIV-1 .PSI. PACKAGING SIGNAL, A REV RESPONSE ELEMENT (RRE), A CENTRAL POLYPURINE TRACT (CPPT) SEQUENCE AND THE WOODCHUCK HEPATITIS VIRUS POST-TRANSCRIPTIONAL REGULATORY ELEMENT (WPRE). THE VECTOR IS PSEUDOTYPED WITH THE ENVELOPE GLYCOPROTEIN (G) OF THE VESICULAR STOMATITIS VIRUS (VSV)

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UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

AZAMIDUGENE AUTOTEMCEL VECTOR

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