DENIKITUG

UNII:	2C6JX7UEN2
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	DENIKITUG
GSRS Full Record:	2C6JX7UEN2 i

2865822-82-6
DENIKITUG [USAN]
Denikitug
Denikitug (immunoglobulin G1-kappa, anti-[Homo sapiens CCR8 (C-C motif chemokine receptor 8, CKR-L1, CDw198)])
Denikitug [WHO-DD]
GS-1811
H-gamma1 heavy chain (1-451) [VH Musmus/Homsap (Mus musculus IGHV10-1*02 (90.9%) -(IGHD) -IGHJ1*01 (82.4%) A120>Q (113)/Homo sapiens IGHV3-73*01 (90.0%) -(IGHD) -IGHJ3*01 (92.9%) M123>T (116), CDR-IMGT [8.10.12] (26-33.51-60.99-110)) (1-121) -Homo sapiens IGHG1*03v, G1m3>G1m17, nG1m1 CH1 K120, CH3 E12, M14 (CH1 R120>K (218) (122-219), hinge 1-15 (220-234), CH2 (235-344), CH3 E12 (360), M14 (362) (345-449), CHS (450-451)) (122-451)], (224-219')-disulfide with L-kappa light chain (1'-219') [V-KAPPA Musmus/Homsap (Mus musculus IGKV2-137*01 (91.3%) -IGKJ1*02 (90.0%) L124>V (109')/Homo sapiens IGKV2-28*01 (89.0%) -IGKJ4*01 (91.7%), CDR-IMGT [11.3.9] (27'-37'.55'-57'.94'-102')) (1'-112') -Homosapiens IGKC*01 (100%), Km3 A45.1 (158'), V101 (196') (113'-219')]; dimer (230-230'':233-233'')-bisdisulfide, produced in a Chinese hamster ovary (CHO) cell line, derived from the cell line CHO-K1SV, co-expressing the enzyme glutamine synthetase (GS), and lacking the enzyme alpha-(1,6)-fucosyltransferase (FUT8), glycoform alfa
Immunoglobulin G1, anti-(human CC chemokine receptor CCR8) (human-Mus musculus monoclonal MO12155MEV γ1-chain), disulfide with human-Mus musculus monoclonal MO12155MEV κ-chain, dimer
JTX-18011
JTX-1811
denikitug [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

DENIKITUG

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