IMDUSIRAN

UNII:	256UZ34AF2
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	IMDUSIRAN
GSRS Full Record:	256UZ34AF2 i

2839476-19-4
AB-729 FREE ACID
IMDUSIRAN [USAN]
Imdusiran
RNA, (Gm-sp-Um-sp-Gm-Cm-(2′-deoxy-2′-fluoro)A-(2′-deoxy-2′-fluoro)C-(2′-deoxy-2′-fluoro)U-Um-Cm-Gm-Cm-Um-Um-Cm-Am-Cm-Am), 3′-[[[rel-(3S,4R)]-1-(9-carboxy-1-oxononyl)-4-(hydroxymethyl)-3,4-dimethyl-3-pyrrolidinyl]methyl hydrogen phosphate], carboxamide with L-glutamoylbis[N-[3,5-bis[[[2-[2-[2-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]ethoxy]ethoxy]ethyl]amino]carbonyl]phenyl]glycinamide], sodium salt, complex with RNA (Um-sp-(2′-deoxy-2′-fluoro)G-sp-Um-Gm-Am-Am-Gm-Cm-Gm-Am-Am-Gm-Um-(2′-deoxy-2′-fluoro)G-Cm-(2′-deoxy-2′-fluoro)A-Cm-Am-Cm-sp-Gm-sp-Gm-U)
[1-(10-{[(S)-1,5-Bis({2-[(3,5-bis{[2-(2-{2-[(2-acetamido-2-deoxy-β-D-galactopyranosyl)oxy]ethoxy}ethoxy)ethyl]carbamoyl}phenyl)amino]-2-oxoethyl}amino)-1,5-dioxopentan-2-yl]amino}-10-oxodecanoyl)-4-(hydroxymethyl)-3,4-dimethylpyrrolidin-3-yl]methyl all-P-ambo-2'-O-methyladenylyl-(3'→5')-2'-O-methylcytidylyl-(3'→5')-2'-O-methyladenylyl-(3'→5')-2'-O-methylcytidylyl-(3'→5')-2'-O-methyluridylyl-(3'→5')-2'-O-methyluridylyl-(3'→5')-2'-O-methylcytidylyl-(3'→5')-2'-O-methylguanylyl-(3'→5')-2'-O-methylcytidylyl-(3'→5')-2'-O-methyluridylyl-(3'→5')-2'-deoxy-2'- fluorouridylyl-(3'→5')-2'- fluorocytidylyl-(3'→5')-2'-deoxy-2'-fluoroadenylyl-(3'→5')-2'-O-methylcytidylyl-(3'→5')-2'-O-methylguanylyl-(3'→5')-2'-O-methyl-P-thiouridylyl-(5'→3')-2'-O-methyl-P-thioguanidine duplex with all-P-ambo-2'-O-methyluridylyl-(5'→3')-2'-O-methyl-P-thioguanylyl-(5'→3')-2'-O-methyl-P-thiouridylyl-(5'→3')-2'-O-methylguanylyl-(5'→3')-2'-O-methyladenylyl-(5'→3')-2'-O-methyladenylyl-(5'→3')-2'-O-methylguanylyl-(5'→3')-2'-O-methylcytidylyl-(5'→3')-2'-O-methylguanylyl-(5'→3')-2'-O-methyladenylyl-(5'→3')-2'-O-methyladenylyl-(5'→3')-2'-O-methylguanylyl-(5'→3')-2'-O-methyluridylyl-(5'→3')-2'-O-methylguanylyl-(5'→3')-2'-O-methylcytidylyl-(5'→3')-2'-O-methyladenylyl-(5'→3')-2'-O-methylcytidylyl-(5'→3')-2'-O-methyladenylyl-(5'→3')-2'-O-methylcytidylyl-(5'→3')-2'-O-methyl-P-thioguanylyl-(5'→3')-2'-O-methyl-P-thioguanylyl-(5'→3')-uridine
imdusiran [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

IMDUSIRAN

Synonyms and Mappings

Resources