AVALOTCAGENE ONTAPARVOVEC

UNII:	20E4R0BF12
Formula:
Preferred Substance Name:	AVALOTCAGENE ONTAPARVOVEC
GSRS Full Record:	20E4R0BF12 i

2227000-30-6
A RECOMBINANT NON-REPLICATING ADENO-ASSOCIATED VIRUS TYPE 2/8 (RAAV REP2-CAP8) VECTOR, ENCODING CODON-OPTIMIZED, WILD-TYPE HUMAN ORNITHINE TRANSCARBAMYLASE (OTC) UNDER THE CONTROL OF A HYBRID HUMAN THYROXINE-BINDING GLOBULIN (TBG) / HUMAN ALPHA 1-MICROGLOBULIN/BIKUNIN PRECURSOR (AMBP) PROMOTER/ENHANCER. THE VECTOR GENOME IS A HEAD-TO-HEAD DIMER, WITH THE VECTOR GENOME CASSETTE LOCATED 5' OF THE MUTATED INTERNAL INVERTED TERMINAL REPEAT (ITR) IN A REVERSE ORIENTATION AND THE VECTOR GENOME CASSETTE LOCATED 3' OF THE MUTATED INTERNAL ITR IN A FORWARD ORIENTATION
AVALOTCAGENE ONTAPARVOVEC [INN]
AVALOTCAGENE ONTAPARVOVEC [USAN]
DTX301
DTX-301
DTX-301 (ORNITHINE-TRANSCARBAMYLASE-GENE-THERAPY)
KFB12DX3PF
SCAAV8OTC

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

AVALOTCAGENE ONTAPARVOVEC

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