DALNICASTOBART

UNII:	1SN6KFW31L
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	DALNICASTOBART
GSRS Full Record:	1SN6KFW31L i

2642171-59-1
Dalnicastobart
Immunoglobulin G1 [de-236-glycine,de-C-terminal lysine], anti-(human CD40 antigen) (human monoclonal LVGN7409 γ1-chain), disulfide with human monoclonal LVGN7409 κ-chain, dimer
Immunoglobulin G1-kappa, anti-[Homo sapiens CD40 (tumor necrosis factor receptor superfamily member 5, TNFRSF5, p50)], Homo sapiens monoclonal antibody, gamma1 heavy chain Homo sapiens (1-454) [VH (Homo sapiens IGHV1-2*02 (98.0%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.19] (26-33.51-58.97-115)) (1-126) -Homo sapiens IGHG1*03v, G1m3>G1m17, nG1m1,G1v47CH2 G1.1del (CH1 R120>K (223) (127-224), hinge 1-15 (225-239), CH2 G1.1>del (240-348), CH3 E12 (364), M14 (366) (349-453), CHS K2>del (454)) (127-454)], (229-214')-disulfide with kappa light chain Homo sapiens (1'-214') [V-KAPPA (Homo sapiens IGKV1-12*01 (94.7%) -IGKJ4*01(100%), CDR-IMGT [6.3.9] (27-32.50-52.89-97)) (1'-107')-Homo sapiens IGKC*01 (100%), Km3, A45.1 (153), V101 (191) (108'-214')]; dimer (235-235'':238-238'')-bisdisulfide, produced in Chinese hamster ovary (CHO) cells, derived from cell line CHO-K1, lacking the glutamine synthetase (GS-KO) gene, glycoform alfa
dalnicastobart [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

DALNICASTOBART

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