PACANALOTAMAB

UNII:	102VUR9WQE
Formula:
Preferred Substance Name:	PACANALOTAMAB
GSRS Full Record:	102VUR9WQE i

2251756-52-0
AMG420
AMG-420
BI-836909
BISPECIFIC T-CELL ENGAGER ANTIBODY WITH A SINGLE CHAIN FC MOIETY THAT BINDS TO B CELL MATURATION ANTIGEN SURFACE RECEPTOR AND CD3
IMMUNOGLOBULIN SCFV-SCFV, ANTI-(HOMO SAPIENS TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 17 (B-CELL MATURATION PROTEIN, CD269 ANTIGEN)) TNR17 AND ANTI-(HOMO SAPIENS T-CELL SURFACE GLYCOPROTEIN CD3 EPSILON CHAIN (T-CELL SURFACE ANTIGEN T3/LEU-4 EPSILON CHAIN, CD3E ANTIGEN)) CD3E; MONOCLONAL ANTIBODY SINGLE CHAIN; BISPECIFIC; VARIABLE CHAINS ANTI-TNR17 (1- 243): (HOMO SAPIENS VH (IGHV1-46*01 (86%) (IGHD)-IGHJ4*01 (93%)) (8.8.14) (1-121)-TRIS(TETRAGLYCYLSERYL) LINKER (122-136), (HOMO SAPIENS VKAPPA (IGKV1-33*01 (92%) IGKJ1*01)) (6.3.9) (137-243),- SERYLTETRAGLYCYLSERYL LINKER (244-249); ANTI-CD3E (250-498): (VH (MUS MUSCULUS IGHV10-1*02 (92%)(IGHD)-IGHJ3*01 (87%)/HOMO SAPIENS IGHV3-73*01 (87%)-(IGHD)-IGHJ5*01)) (8.10.16) (250-374)- TRIS(TETRAGLYCYLSERYL) LINKER (375-389) V-LAMBDA (HOMO SAPIENS IGLV7-43*01 (85%) IGLJ3*02) (9.3.9) (390-498) PENTAHISTIDYLHISTIDINE (499-504), NONGLYCOSYLATED, PRODUCED IN CHO CELLS
IMMUNOGLOBULIN SCFV-SCFV, ANTI-(HOMO SAPIENSTNFRSF17 (TNF RECEPTOR SUPERFAMILY MEMBER 17, TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY, MEMBER 17, B CELL MATURATION ANTIGEN, BCMA, BCM, TNFRSF13A, CD269)) AND ANTI-(HOMO SAPIENS CD3E (CD3 EPSILON)), MONOCLONAL ANTIBODY SINGLE CHAIN, BISPECIFIC
IMMUNOGLOBULIN, ANTI-(HUMAN TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY PROTEIN TNFRSF17) (HUMAN MONOCLONAL BRA-KAN 1 SINGLE-CHAIN VARIABLE FRAGMENT VH1-(GGGGS)3-VL1) FUSION PROTEIN WITH PEPTIDE LINKER (GGGGS) FUSION PROTEIN WITH IMMUNOGLOBULIN ANTI-(HUMAN CD3 ANTIGEN .EPSILON.-CHAIN) (HUMAN MONOCLONAL BRA-KAN 1 SINGLE-CHAIN VARIABLE FRAGMENT VH2-(GGGGS)3-VL2) FUSION PROTEIN WITH HEXAHISTIDINE TAG
PACANALOTAMAB [INN]
PACANALOTAMAB [USAN]
PACANALOTAMAB [WHO-DD]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

PACANALOTAMAB

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