LEMZOPARLIMAB

UNII:	0H2XLR2IKW
Type:	INGREDIENT SUBSTANCE
Formula:
Preferred Substance Name:	LEMZOPARLIMAB
GSRS Full Record:	0H2XLR2IKW i

2377483-71-9
Immunoglobulin G4[228-proline], anti-(human CD47 antigen) (human monoclonal TJ011133 γ4-chain), disulfide with human monoclonal TJ011133 κ-chain, dimer
LEMZOPARLIMAB [USAN]
Lemzoparlimab [WHO-DD]
TJ-011133
TJ011133
immunoglobulin G4-kappa, anti-[Homo sapiens CD47 (integrin associated protein, IAP, MER6, OA3)], monoclonal antibody; gamma4 heavy chain (1-445) [VH (Homo sapiens IGHV3-15*07 (93.9%) -(IGHD) -IGHJ3*02 (100%)) CDR-IMGT [8.10.9] (26-33.51-60.99-107) (1-118) -Homo sapiens IGHG4*01 (100%), G4v5 h P10 (CH1 (119-216), hinge 1-12 S10>P (226) (217-228), CH2 (229-338), CH3 (339-443), CHS (444-445)) (119-445)], (132-220')-disulfide with kappa light chain (1'-220') [V-KAPPA (Homo sapiens IGKV4-1*01 (89.1%) -IGKJ2*01 (90%) Q120>G (106)) CDR-IMGT [12.3.9] (27-38.56-58.95-103) (1'-113') -Homo sapiens IGKC*01 (100%), Km3 A45.1 (159), V101 (197) (114'-220')]; dimer (224-224'':227-227'')-bisdisulfide, produced in a Chinese hamster ovary (CHO)-K1 cell line, glycoform alfa
lemzoparlimab [INN]

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.

LEMZOPARLIMAB

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