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TISOTUMAB VEDOTIN

  • UNII: T41737F88A
  • Preferred Substance Name: TISOTUMAB VEDOTIN

  • 1418731-10-8
  • GCT1015-04
  • HUMAX-TF-ADC
  • IGG1-1015-011-1006
  • IMMUNOGLOBULIN G1, ANTI-(HUMAN BLOOD-COAGULATION FACTOR III) (HUMAN MONOCLONAL HUMAX-TF HEAVY CHAIN), DISULFIDE WITH HUMAN MONOCLONAL HUMAX-TF .KAPPA.-CHAIN, DIMER, TETRAKIS(THIOETHER) WITH N-(((4-((N-(6-(3-MERCAPTO-2,5-DIOXO-1-PYRROLIDINYL)-1-OXOHEXYL)-L-VALYL-N5-(AMINOCARBONYL)-L-ORNITHYL)AMINO)PHENYL)METHOXY)CARBONYL)-N-METHYL-L-VALYL-N-((1S,2R)-4-((2S)-2-((1R,2R)-3-(((1R,2S)-2-HYDROXY-1-METHYL-2-PHENYLETHYL)AMINO)-1-METHOXY-2-METHYL-3-OXOPROPYL)-1-PYRROLIDINYL)-2-METHOXY-1-((1S)-1-METHYLPROPYL)-4-OXOBUTYL)-N-METHYL-L-VALINAMIDE
  • IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS TISSUE FACTOR (COAGULATION FACTOR III, THROMBOPLASTIN, CD142 ANTIGEN, TF))HOMO SAPIENS MONOCLONAL ANTIBODY.GAMMA.1 HEAVY CHAIN (1-448) (HOMO SAPIENS VH (IGHV3-23*01 (94%) (IGHD)-IGHJ5*01 (87%)) (8.8.11) (1-118)-HOMO SAPIENS IGHG1*03) (119-448)), (221-214')-DISULFIDE WITH .KAPPA. LIGHT CHAIN (1'-214') (HOMO SAPIENS V-KAPPA (IGKV1D-16*01 (97%) IGKJ2*01)(6.3.9) (1'-107')-HOMO SAPIENS IGKC*01 (108'-214')), DIMER (227-227'':230-230'')-BISDISULFIDE, S-SUBSTITUTED ON AN AVERAGE OF 3 TO 4 CYSTEINYL, AFTER PARTIAL REDUCTION OF THE TISOTUMAB, BY VEDOTIN RADICALS : (3RS)-1-(6-(((2S)-1-(((2S)-5-(CARBAMOYLAMINO)-1-(4-(((((2S)-1-(((2S)-1-(((3R,4S,5S)-1-((2S)-2-((1R,2R)-3-(((1S,2R)-1-HYDROXY-1-PHENYLPROPAN-2-YL)AMINO)-1-METHOXY-2-METHYL-3-OXOPROPYL)PYRROLIDIN-1-YL)-3-METHOXY-5-METHYL-1-OXOHEPTAN-4-YL)(METHYL)AMINO)-3-METHYL-1-OXOBUTAN-2-YL)AMINO)-3-METHYL-1-OXOBUTAN-2-YL)METHYLCARBAMOYL)OXY)METHYL)ANILINO)-1-OXOPENTAN-2-YL)AMINO)-3-METHYL-1-OXOBUTAN-2-YL)AMINO)-6-OXOHEXYL)-2,5-DIOXOPYRROLIDIN-3-YL
  • TF-011-MMAE
  • TISOTUMAB VEDOTIN [INN]
  • TISOTUMAB VEDOTIN [JAN]
  • TISOTUMAB VEDOTIN [USAN]
  • TISOTUMAB VEDOTIN [WHO-DD]
  • TISOTUMAB VEDOTIN TFTV [WHO-DD]
  • TISOTUMAB VEDOTIN-TFTV
  • TIVDAK

Note

UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements. UNII availability does not imply any regulatory review or approval. Synonyms and mappings are based on the best public information available at the time of publication. Please report any problems/errors associated with this data to FDA-SRS@fda.hhs.gov.